Background: The aim of this study was to examine the Tpeak-Tend (Tpe/corrected Tpe) interval, which is an\nindicator of transmural myocardial repolarization, measured non-invasively via electrocardiogram in patients with acute\npulmonary embolism (PE), and to investigate the relationship with 30-day mortality and morbidity.\nMethods: The study included 272 patients diagnosed with acute PE, comprising 154 females and 118 males,\nwith a mean age of 63.1 Ã?± 16.8 years. Tpe/cTpe intervals were calculated from the electrocardiograms with a computer\nprogram after using a ruler or vernier caliper manual measuring tool to obtain highly sensitive measurements.\nThe relationship between the electrocardiogram values and 30-days mortality and morbidity were measured.\nResults: The study group was divided into three groups according to cTpe intervals: Group 1, < 113 ms; Group 2,\n113ââ?¬â??133 ms; and Group 3, > 133 ms. White blood cell count and troponin T levels, corrected QT intervals with QRS\ncomplex durations, percentage of right ventricle dilatation with right/left-ventricular ratio, 30-day death, and\ncombinations of these values were seen at a higher rate in Group 3 patients compared to the other groups.\nKaplanââ?¬â??Meier analysis showed that the cTpe interval measured at > 126 ms could be used as a cut-off value\nin the prediction of mortality and morbidity. The cTpe cut-off values of 126 ms had sensivity, specificity, negative\npredictive value, and positive predictive value of 80.56 %, 59.32 %, 95.2 %, and 23.2 %, respectively.\nConclusions: cTpe interval could be a useful method in early risk stratification in patients with acute PE.
Loading....